Item no. |
HY-N0005S-1mg |
Manufacturer |
MedChem Express
|
CASRN |
1246833-26-0 |
Amount |
1 mg |
Quantity options |
10 mg
1 ea
1 mg
5 mg
|
Category |
|
Type |
Molecules |
Specific against |
other |
Citations |
[1]Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004.<br/>[2]Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53.<br/>[3]Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4.<br/>[4]Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4.<br/>[5]Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303. |
Smiles |
O=C(CC(/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1)=O)/C=C/C2=CC=C(O)C(OC([2H])([2H])[2H])=C2 |
ECLASS 10.1 |
32169090 |
ECLASS 11.0 |
32169090 |
UNSPSC |
12000000 |
Alias |
Diferuloylmethane-d6; Natural Yellow 3-d6; Turmeric yellow-d6 |
Available |
|
Product Description |
Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs. |
Shipping |
Room temperature |
Manufacturers Applications |
Cancer-programmed cell death |
MolecularWeight |
374.42 |
Clinical Information |
No Development Reported |
Manufacturers Research Area |
Infection; Metabolic Disease; Inflammation/Immunology |
Solubility |
10 mM in DMSO |
Target |
Autophagy; Epigenetic Reader Domain; Ferroptosis; Histone Acetyltransferase; Influenza Virus; Keap1-Nrf2; Mitophagy |
Manufacturers Target |
Autophagy; Epigenetic Reader Domain; Ferroptosis; Histone Acetyltransferase; Influenza Virus; Keap1-Nrf2; Mitophagy |
Isoform |
CBP/p300 |
Manufacturers Pathway |
Anti-infection; Apoptosis; Autophagy; Epigenetics; NF-κB |
Manufacturers Product type |
Isotope-Labeled Compounds |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.