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Oxidopamine (hydrochloride)

Oxidopamine (hydrochloride)

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Amount	10 mg
Item no.	HY-B1081-10mg
CASRN	28094-15-7
eClass 6.1	30220300
eClass 9.0	32160605
Available
Alias	6-Hydroxydopamine hydrochloride; 6-OHDA hydrochloride
Purity	99.91
Product Description	Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome[1][2][3][4].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	205.64
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Neurological Disease
Solubility	DMSO : 83.33 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturers Target	Apoptosis; Autophagy; Caspase; COX; Dopamine Receptor; Interleukin Related; Mitophagy; p38 MAPK; PGE synthase
Isoform	Caspase 3; Caspase 8; Caspase 9; COX-2; IL-1
Pathway	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Neuronal Signaling
Manufacturers Product type	Reference compound

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