Item no. |
HY-B0688-500mg |
Manufacturer |
MedChem Express
|
CASRN |
80-08-0 |
Amount |
500 mg |
Quantity options |
10mM/1mL
1 g
500 mg
5 g
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
99.67 |
Formula |
C12H12N2O2S |
Citations |
[1]D Voeller, et al. Interaction of Pneumocystis carinii dihydropteroate synthase with sulfonamides and diaminodiphenyl sulfone (dapsone).J Infect Dis. 1994 Feb;169(2):456-9.<br>[2]Esther Moreno, et al. Evaluation of Skin Permeation and Retention of Topical Dapsone in Murine Cutaneous Leishmaniasis Lesions.Pharmaceutics. 2019 Nov 13;11(11):607.<br>[3]Y I Zhu, et al. Dapsone and sulfones in dermatology: overview and update. J Am Acad Dermatol<br>[4]Dapsone, Drug.com |
Smiles |
O=S(C1=CC=C(N)C=C1)(C2=CC=C(N)C=C2)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
4,4′-Diaminodiphenyl sulfone; DDS |
Available |
|
Product Description |
Dapsone (4, 4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities[1]. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al[2][3]. |
StorageTemperature |
-20°C, 3 years; 4°C, 2 years (Powder) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
248.30 |
Clinical_Information |
Launched |
Manufacturers Research Area |
Infection; Inflammation/Immunology |
Solubility |
DMSO : 250 mg/mL (ultrasonic) |
Manufacturers Target |
Antibiotic; Bacterial; Parasite; Reactive Oxygen Species |
Pathway |
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.