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Propofol-d18

Propofol-d18

Item no.	HY-B0649S1-1ea
Manufacturer	MedChem Express
CASRN	1189467-93-3
Amount	1ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	96.98
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. <br>[2]R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid(A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282(3):1181-6.
Smiles	[2H]C([2H])([2H])C(C1=C(C(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=C([2H])C([2H])=C1[2H])O[2H])([2H])C([2H])([2H])[2H]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Propofol-d18 is the deuterium labeled Propofol. Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	196.38
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturers Target	Endogenous Metabolite; GABA Receptor
Pathway	Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Manufacturers Product type	Isotope-Labeled Compounds

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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