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Dexrazoxane

Dexrazoxane

Item no.	HY-B0581-25mg
Manufacturer	MedChem Express
CASRN	24584-09-6
Amount	25 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.88
Formula	C11H16N4O4
Citations	Adv Sci (Weinh). 2023 Mar 26;e2206007. Biochem Pharmacol. 2024 Apr 30:224:116247. Biomed Pharmacother. 2022 Jun 17;153:113280. Cardiovasc Toxicol. 2024 Jun 19. Free Radic Biol Med. 2020 Nov 20;160:303-318. Mol Med Rep. 2024 May;29(5):84. Nano Res. 2023 Apr 18. Phytomedicine. 2023 Jun 10, 154922. Environ Toxicol Pharmacol. 2023 Sep 7;104261. Nat Med. 2016 May;22(5):547-56. [1]Jones, R.L., Utility of dexrazoxane for the reduction of anthracycline-induced cardiotoxicity. Expert Rev Cardiovasc Ther, 2008. 6(10): p. 1311-7. [2]Loyevsky, M., et al., Plasmodium falciparum and Plasmodium yoelii: effect of the iron chelation prodrug dexrazoxane on in vitro cultures. Exp Parasitol, 1999. 91(2): p. 105-14.
Smiles	C[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ICRF-187; ADR-529; NSC-169780
Available
Product Description	Dexrazoxane (ICRF-187) is a cardioprotective agent.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	268.27
Clinical Information	Launched
Manufacturers Research Area	Cardiovascular Disease; Cancer
Solubility	DMSO : 25 mg/mL (ultrasonic)
Target	Others
Manufacturers Target	Others
Manufacturers Pathway	Others
Manufacturers Product type	Reference compound

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