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Ketoprofen-d3

Ketoprofen-d3

Item no.	HY-B0227S-10mg
Manufacturer	MedChem Express
CASRN	159490-55-8
Amount	10 mg
Quantity options	10 mg 1ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.0
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. <br/>[2]Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12(4):533-7.
Smiles	O=C(C1=CC=CC=C1)C2=CC(C(C([2H])([2H])[2H])C(O)=O)=CC=C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	RP-19583-d3
Available
Product Description	Ketoprofen-d3 is the deuterium labeled Ketoprofen. Ketoprofen (RP-19583) is a non-steroidal antiinflammatory agent, acting as a potent inhibitor of COX, with IC50s of 2 nM and 26 nM for COX-1 and COX-2 in human blood monocytes, respectively[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
MolecularWeight	257.30
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Apoptosis; COX
Manufacturers Target	Apoptosis; COX
Manufacturers Pathway	Apoptosis; Immunology/Inflammation
Manufacturers Product type	Isotope-Labeled Compounds

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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