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Candesartan-d5

Candesartan-d5

Item no.	HY-B0205S1-1mg
Manufacturer	MedChem Express
CASRN	1189650-58-5
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	95.50
Formula	C24H15D5N6O3
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. <br>[2]Pfeffer MA, et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet. 2003 Sep 6;362(9386):759-66.<br>[3]Nishimura Y, et al. Chronic peripheral administration of the angiotensin II AT(1) receptor antagonist candesartan blocks brain AT(1) receptors. Brain Res. 2000 Jul 14;871(1):29-38.
Smiles	[2H]C([2H])([2H])C([2H])([2H])OC1=NC2=CC=CC(C(O)=O)=C2N1CC3=CC=C(C4=C(C5=NN=NN5)C=CC=C4)C=C3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Candesartan-d5 is the deuterium labeled Candesartan. Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM.
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
MolecularWeight	445.48
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cardiovascular Disease; Endocrinology; Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Angiotensin Receptor; Isotope-Labeled Compounds
Pathway	GPCR/G Protein; Others
Manufacturers Product type	Isotope-Labeled Compounds

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