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Nebivolol (hydrochloride)

Nebivolol (hydrochloride)

Item no.	HY-B0203A-100mg
Manufacturer	MedChem Express
CASRN	152520-56-4
Amount	100 mg
Quantity options	100 mg 10mM/1mL 10 mg 500 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.89
Formula	C22H26ClF2NO4
Citations	Virology. 2023 Jun 21.<br/>J Pharmaceut Biomed. 2020, 113870.<br/>[1]Brehm BR, et al. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovasc Res. 2001 Feb 1;49(2):430-9.<br/>[2]Thomas Münzel, et al. Nebivolol: the somewhat-different beta-adrenergic receptor blocker. J Am Coll Cardiol. 2009 Oct 13;54(16):1491-9.
Smiles	FC1=CC=C2C(CC[C@]([C@@H](O)CNC[C@H](O)[C@@]3([H])CCC(C=C(F)C=C4)=C4O3)([H])O2)=C1.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	R 065824 hydrochloride
Available
Product Description	Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease[1][2].
StorageTemperature	4°C (Powder, sealed storage, away from moisture)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	441.90
Clinical Information	Launched
Manufacturers Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 1.79 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Adrenergic Receptor
Manufacturers Target	Adrenergic Receptor
Manufacturers Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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HY-B0203A-100mg-safety-datasheet.pdf