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Cefaclor

Cefaclor

Item no.	HY-B0198-500mg
Manufacturer	MedChem Express
CASRN	53994-73-3
Amount	500 mg
Quantity options	10mM/1mL 1 g 500 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.61
Formula	C15H14ClN3O4S
Citations	[1]Joo MK, et al. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice. Sci Rep. 2023 Sep 19;13(1):15529. <br/>[2]Li M, et al. Interactions of amoxicillin and cefaclor with human renal organic anion and peptide transporters. Drug Metab Dispos. 2006 Apr;34(4):547-55. <br/>[3]Yoo HS, et al. Immunologic evaluation of immediate hypersensitivity to cefaclor. Yonsei Med J. 2014 Nov;55(6):1473-83. <br/>[4]Neu HC, et al. Cefaclor: in vitro spectrum of activity and beta-lactamase stability. Antimicrob Agents Chemother. 1978 Apr;13(4):584-8.
Smiles	O=C(C(N12)=C(Cl)CS[C@]2([H])[C@H](NC([C@H](N)C3=CC=CC=C3)=O)C1=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	53994-73-3
Available
Product Description	Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections[1][2][3][4].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	367.81
Clinical Information	Launched
Manufacturers Research Area	Infection; Inflammation/Immunology; Neurological Disease
Solubility	DMSO : 18.5 mg/mL (ultrasonic; warming)\|H2O : 3.85 mg/mL (ultrasonic)
Target	5-HT Receptor; Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Manufacturers Target	5-HT Receptor; Antibiotic; Bacterial; Penicillin-binding protein (PBP)
Isoform	5-HT Receptor; β-lactam
Manufacturers Pathway	Anti-infection; GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0198-500mg-safety-datasheet.pdf