Item no. |
HY-B0131-1mg |
Manufacturer |
MedChem Express
|
CASRN |
745-65-3 |
Amount |
1 mg |
Quantity options |
10mM*1 mL
10 mg
1 mg
50 mg
5 mg
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.81 |
Formula |
C20H34O5 |
Citations |
[1]Kiriyama M, et, al. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol. 1997 Sep;122(2):217-24.<br/>[2]Cattaneo MG, et, al. Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay. Br J Pharmacol. 2003 Jan;138(2):377-85.<br/>[3]Hauck EW, et, al. Prostaglandin E1 long-term self-injection programme for treatment of erectile dysfunction--a follow-up of at least 5 years. Andrologia. 1999;31 Suppl 1:99-103. |
Smiles |
CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
Alprostadil; PGE1 |
Available |
|
Product Description |
Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases[1][2][3]. |
StorageTemperature |
4°C (Powder, stored under nitrogen) |
Shipping |
Room Temperature |
Manufacturers Applications |
Metabolism-protein/nucleotide metabolism |
MolecularWeight |
354.48 |
Clinical Information |
Launched |
Manufacturers Research Area |
Endocrinology; Cardiovascular Disease; Cancer |
Solubility |
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic) |
Target |
Endogenous Metabolite; Prostaglandin Receptor |
Manufacturers Target |
Endogenous Metabolite; Prostaglandin Receptor |
Isoform |
EP; Human Endogenous Metabolite |
Manufacturers Pathway |
GPCR/G Protein; Metabolic Enzyme/Protease |
Manufacturers Product type |
Natural Products |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.