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Oxcarbazepine-d4

Oxcarbazepine-d4

Item no.	HY-B0114S-25mg
Manufacturer	MedChem Express
CASRN	1020719-71-4
Amount	25 mg
Quantity options	2.5mg 25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C15H8D4N2O2
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.<br/>[2]Ashley M Thomas, et al. Old Friends With New Faces: Are Sodium Channel Blockers the Future of Adjunct Pain Medication Management?J Pain. 2018 Jan;19(1):1-9.<br/>[3]Ching-Yi Lee,et al. The effects of antiepileptic drugs on the growth of glioblastoma cell lines. J Neurooncol. 2016 May;127(3):445-53.<br/>[4]M Schmutz, et al. Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action. Epilepsia. 1994;35 Suppl 5:S47-50.
Smiles	C(N)(=O)N1C=2C(C(=O)CC=3C1=C(C(=C(C3[2H])[2H])[2H])[2H])=CC=CC2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	GP 47680-D4
Available
Product Description	Oxcarbazepine-d4 (GP 47680-D4) is the deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Anti-cancer and anticonvulsant effects[2][3].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	256.29
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Neurological Disease
Solubility	10 mM in DMSO
Target	Apoptosis; Isotope-Labeled Compounds; Sodium Channel
Manufacturers Target	Apoptosis; Isotope-Labeled Compounds; Sodium Channel
Manufacturers Pathway	Apoptosis; Membrane Transporter/Ion Channel; Others
Manufacturers Product type	Isotope-Labeled Compounds

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Amount: 25 mg

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