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Pamidronic acid

Pamidronic acid

Item no.	HY-B0012-100mg
Manufacturer	MedChem Express
CASRN	40391-99-9
Amount	100 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.00
Formula	C3H11NO7P2
Citations	[1]Ashton JA, et al. Investigation of the effect of pamidronate disodium on the in vitro viability of osteosarcoma cellsfrom dogs. Am J Vet Res. 2005 May;66(5):885-91.<br>[2]Xu Y, et al. Pamidronate Disodium Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells In Vitro. J Oral Maxillofac Surg. 2017 Mar 22.<br>[3]Lv Y, et al. Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits. BMC Musculoskelet Disord. 2014 Nov 6;15:370.
Smiles	OC(P(O)(O)=O)(P(O)(O)=O)CCN
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Pamidronic acid is a agent used to treat a broad spectrum of bone absorption diseases.
StorageTemperature	-20°C (Powder, protect from light)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	235.07
Clinical_Information	Launched
Manufacturers Research_Area	Cancer; Metabolic Disease; Inflammation/Immunology
Solubility	DMSO : < 1 mg/mL\|H2O : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Manufacturers Target	Bacterial; Wnt; β-catenin
Pathway	Anti-infection; Stem Cell/Wnt
Manufacturers Product type	Reference compound

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