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Nitrofurantoin

Nitrofurantoin

Item no.	HY-A0090-500mg
Manufacturer	MedChem Express
CASRN	67-20-9
Amount	500 mg
Quantity options	10mM/1mL 1 g 500 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Formula	C8H6N4O5
Citations	[1]Linus Sandegren, et al. Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli. J Antimicrob Chemother. 2008 Sep;62(3):495-503.<br/>[2]Xiaodong Wang, et al. Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab Dispos. 2007 Feb;35(2):268-74.<br/>[3]Huttner A, et al. Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. J Antimicrob Chemother. 2015 Sep;70(9):2456-64.<br/>[4]Garau J. Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline. Clin Microbiol Infect. 2008 Jan;14 Suppl 1:198-202.
Smiles	O=C1NC(CN1/N=C/C2=CC=C([N+]([O-])=O)O2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	67-20-9
Available
Product Description	Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	238.16
Clinical Information	Launched
Manufacturers Research Area	Infection
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Antibiotic; Bacterial
Manufacturers Target	Antibiotic; Bacterial
Isoform	β-lactam
Manufacturers Pathway	Anti-infection
Manufacturers Product type	Reference compound

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HY-A0090-500mg-safety-datasheet.pdf