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4',5'-Didehydro-5'-deoxyuridine

4',5'-Didehydro-5'-deoxyuridine

Item no.	HY-77645-1ea
Manufacturer	MedChem Express
CASRN	14365-63-0
Amount	1 ea
Quantity options	100 mg 10mM/1mL 10 mg 1 ea 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	95.0
Formula	C9H10N2O5
Citations	[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Smiles	C=C1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)uracil
Available
Product Description	4', 5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	226.19
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Nucleoside Antimetabolite/Analog
Manufacturers Target	Nucleoside Antimetabolite/Analog
Manufacturers Pathway	Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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