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Enzalutamide carboxylic acid

Enzalutamide carboxylic acid

Item no.	HY-70002B-10mM
Manufacturer	MedChem Express
CASRN	1242137-15-0
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	98.11
Formula	C20H13F4N3O3S
Citations	[1]van Nuland M, et al. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy. 2019 Dec;39(12):1137-1145.
Smiles	O=C(O)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	MDV3100 carboxylic acid
Available
Product Description	Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	451.39
Clinical_Information	Launched
Manufacturers Research_Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturers Target	Drug Metabolite
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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Amount: 10mM/1mL

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