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(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate

Item no.	HY-49556-100mg
Manufacturer	MedChem Express
CASRN	2414393-48-7
Amount	100 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.69
Formula	C12H14O3
Citations	[1]Li Zhen, et al. Camptothecin derivative, and pharmaceutical composition and use thereof. World Intellectual Property Organization, WO2023020605 A1. 2023-02-23. [2]Huang Q, et al. Evolution in medicinal chemistry of E-ring-modified Camptothecin analogs as anticancer agents. Eur J Med Chem. 2013;63:746-757.
Smiles	O=C(OCC1=CC=CC=C1)[C@H](C2CC2)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Others
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	206.24
Product Description	(S)-Benzyl 2-cyclopropyl-2-hydroxyacetate is an intermediate reactant in the synthesis of Camptothecin (HY-16560). Camptothecin is an inhibitor of the DNA topoisomerase Topo I, withIC50=679 nM[1][2].
Manufacturer - Research Area	cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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HY-49556-100mg-safety-datasheet.pdf