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Izilendustat

Izilendustat

Item no.	HY-44809-5mg
Manufacturer	MedChem Express
CASRN	1303512-02-8
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.20
Formula	C22H28ClN3O4
Citations	[1]Joseph H, et al. Prolyl hydroxylase inhibitors. Patent WO2011057115A1. <br/>[2]Joseph H, et al. Compositions and methods for treating colitis. Patent WO2011057121A1.
Smiles	O=C(N1CCN(CC(C=CN2CC3=CC=C(Cl)C=C3)=C(O)C2=O)CC1)OC(C)(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Izilendustat is a potent inhibitor of prolyl hydroxylase which can stabilize hypoxia inducible factor- 1 alpha (HIF- lα) and hypoxia inducible factor-2 (HIF-2). Izilendustat has the potential for researching diseases that relate to the body’s inmmune response like colitis and other inflammatory bowel diseases (extracted from patent WO2011057115A1 and WO2011057121A1)[1][1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	433.93
Clinical Information	No Development Reported
Manufacturers Research Area	Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Target	HIF/HIF Prolyl-Hydroxylase
Manufacturers Target	HIF/HIF Prolyl-Hydroxylase
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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