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cis-ACPD

cis-ACPD

Item no.	HY-19434A-1ea
Manufacturer	MedChem Express
CASRN	477331-06-9
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Formula	C7H11NO4
Citations	[1]Schoepp DD, et, al. In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: dissociation of metabotropic and ionotropic excitatory amino acid receptor effects. J Neurochem. 1991 May; 56(5):1789-96.<br/>[2]Conti P, et, al. Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid. Farmaco. 2002 Nov; 57(11): 889-95.
Smiles	O=C([C@]1(N)C[C@H](C(O)=O)CC1)O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	cis-ACPD is a potent agonist of NMDA receptor, with an IC50 of 3.3 μM. cis-ACPD is also a selective agonist of group II mGluR, with EC50s of 13 μM and 50 μM for mGluR2 and mGluR4, respectively[1][2].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	173.17
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	10 mM in DMSO
Target	iGluR; mGluR
Manufacturers Target	iGluR; mGluR
Isoform	mGluR2; mGluR4; NMDA Receptor
Manufacturers Pathway	GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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