Item no. |
HY-17002-50mg |
Manufacturer |
MedChem Express
|
CASRN |
94055-76-2 |
Amount |
50 mg |
Quantity options |
100 mg
10 mM/1 mL
10 mM/1 mL
500 mg
50 mg
|
Category |
|
Type |
Inhibitors |
Specific against |
other |
Purity |
98.33 |
Formula |
C23H33NO7S2 |
Citations |
[1]Furonaka M, Hattori N, Tanimoto T, Senoo T, Ishikawa N, Fujitaka K, Haruta Y, Yokoyama A, Kohno N.
<br>Suplatast tosilate prevents bleomycin-induced pulmonary fibrosis in mice.
<br>J Pharmacol Exp Ther. 2009 Jan;328(1):55-61.<br/>[2]Yanagihara Y, et, al. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2). Regulation of human IgE response. Jpn J Pharmacol. 1993 Jan;61(1):31-9.<br/>[3]Zhao GD, et, al. Effect of suplatast tosilate (IPD-1151T) on a mouse model of asthma: inhibition of eosinophilic inflammation and bronchial hyperresponsiveness. Int Arch Allergy Immunol. 2000 Feb;121(2):116-22.<br/>[4]Kurokawa M, et, al. Suppressive effects of anti-allergic agent suplatast tosilate (IPD-1151T) on the expression of co-stimulatory molecules on mouse splenocytes in vivo. Mediators Inflamm. 2001 Dec;10(6):333-7. |
Smiles |
C[S+](C)CCC(NC1=CC=C(C=C1)OCC(COCC)O)=O.CC2=CC=C(C=C2)S(=O)([O-])=O |
ECLASS 10.1 |
32160490 |
ECLASS 11.0 |
32160490 |
UNSPSC |
12000000 |
Alias |
IPD 1151T |
Available |
|
Product Description |
Suplatast Tosilate (IPD 1151T) is an orally active Th2 cytokine inhibitor which can inhibit both IL-4 and IL-5 production from Th2 cells and suppress IgE synthesis. Suplatast Tosilate is an anti-allergic agent. Suplatast Tosilate has antiasthmatic, anti-inflammatory and antifibrotic activity[1][2][3][4]. |
StorageTemperature |
4°C (Powder, sealed storage, away from moisture) |
Shipping |
Room Temperature |
Manufacturers Applications |
COVID-19-immunoregulation |
MolecularWeight |
499.64 |
Clinical Information |
Launched |
Manufacturers Research Area |
Inflammation/Immunology |
Solubility |
DMSO : ≥ 33 mg/mL|H2O : ≥ 100 mg/mL |
Target |
Interleukin Related |
Manufacturers Target |
Interleukin Related |
Isoform |
IL-13; IL-2; IL-4; IL-5 |
Manufacturers Pathway |
Immunology/Inflammation |
Manufacturers Product type |
Reference compound |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.