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Dapaconazole

Dapaconazole

Item no.	HY-16719-25mg
Manufacturer	MedChem Express
CASRN	1269726-67-1
Amount	25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.95
Formula	C19H15Cl2F3N2O
Citations	[1]Juliana SP, et al. Pharmacokinetics of Dapaconazole, A Novel Antifungal Agent, in Beagle Dogs and Inhibition of Cytochrome P450 Family 51. J Eur Acad Dermatol Venereol. 2018 Jun 10.
Smiles	FC(C1=CC=C(COC(C2=CC=C(Cl)C=C2Cl)CN3C=CN=C3)C=C1)(F)F
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC50 of 1.4 μM[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	415.24
Clinical_Information	Phase 3
Manufacturers Research_Area	Infection
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Cytochrome P450
Isoform	CYP26
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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