« Back
Home /
NICE-01

NICE-01

Item no.	HY-156214-5mg
Manufacturer	MedChem Express
CASRN	2982819-94-1
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.53
Formula	C63H76ClN7O13S
Citations	[1]William J. Gibson, et al. Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. Version 1. bioRxiv. Preprint. 2023 Jul 7.
Smiles	CC(C(C(C(C=C1)=CC=C1Cl)=N[C@H]2CC(NCCOCCOCCNC(COC3=CC([C@@H](CCC(C=C4)=CC(OC)=C4OC)OC([C@H](CCCC5)N5C([C@H](C(C=C6OC)=CC(OC)=C6OC)CC)=O)=O)=CC=C3)=O)=O)=C(S7)N8C2=NN=C8C)=C7C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AP1867-PEG2-JQ1; AP-PEG2-JQ1
Available
Product Description	NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that bind to proteins in separate cellular compartments that can induce nuclear import of cytosolic cargoes, using nuclear-localized bromodomain-containing protein 4 (BRD4) as a “carrier” for co-import and nuclear trapping of cytosolic proteins[1].
StorageTemperature	-20°C (Powder, sealed storage, away from moisture and light)
Shipping	Blue Ice
MolecularWeight	1206.83
Clinical_Information	No Development Reported
Manufacturers Research_Area	others
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5 mg

available

Request delivery time