M826

Item no.	HY-155612-1ea
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C28H45N7O6
Citations	[1]Han BH, et al. Selective, reversible caspase-3 inhibitor is neuroprotective and reveals distinct pathways of cell death after neonatal hypoxic-ischemic brain injury. J Biol Chem. 2002 Aug 16;277(33):30128-36.
Smiles	O=C1N(C=C(N=C1NCC2=NON=C2C)C(C)(C)C)[C@H](C(N[C@H](C(CN(CCCCCC)C)=O)CC(O)=O)=O)CC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	M826 is a potent, selective and reversible non-peptide caspase-3 inhibitor with an IC50 value of 0.005 μM for enzymatic activity against caspase-3. M826 displays potent anti-apoptotic activity in animal models in vitro and in vivo. M826 can be used for nervous system diseases research[1].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neurodegeneration
MolecularWeight	575.70
Clinical Information	No Development Reported
Manufacturers Research Area	Neurological Disease
Solubility	10 mM in DMSO
Target	Caspase
Manufacturers Target	Caspase
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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