A4333

Item no.	HY-155343
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C28H26F6N6O4S
Citations	[1]Won Chan Hwang, et al. Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer.Exp Mol Med. 2022 Sep;54(9):1563-1576.
Smiles	O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)C2=CC3=C(N2)C=CC(C(NNC(CCCC[C@H]4[C@](NC(N5)=O)([H])[C@]5([H])CS4)=O)=O)=C3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	A4333 is biotinylated compound of A3373 (HY-155342) that inhibits Phospholipase D1 (PLD1), but not PLD2. A4333 plays an important role in antitumor activity[1].
Shipping	Room temperature
MolecularWeight	656.60
Clinical_Information	No Development Reported
Manufacturers Research_Area	cancer
Solubility	10 mM in DMSO
Manufacturers Target	Phospholipase
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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