Comparison

SARS-CoV-2 3CLpro-IN-19 European Partner

Item no. HY-155186-1ea
Manufacturer MedChem Express
Amount 1 ea
Category
Type Inhibitors
Specific against other
Formula C24H22ClN3O2S
Citations [1]Pérez-Vargas J, et al. A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect. 2023 Dec;12(2):2246594.
Smiles CN(C)C1=CC=C(N(C(CC2=C(C(O)=CC=C3)C3=CN=C2)=O)CC4=CC(Cl)=CS4)C=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
SARS-CoV-2 3CLpro-IN-19 (Compound C5a) is a non-covalent, non-peptide SARS-CoV-2 3CLpro inhibitor (IC50s: 0.7 μM). SARS-CoV-2 3CLpro-IN-19 has broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) infection in human cells, with EC50 values between 30-69 nM[1].
Shipping
Room temperature
Manufacturers Applications
COVID-19-anti-virus
MolecularWeight
451.97
Clinical Information
No Development Reported
Manufacturers Research Area
Infection
Solubility
10 mM in DMSO
Target
SARS-CoV
Manufacturers Target
SARS-CoV
Manufacturers Pathway
Anti-infection
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 ea
Available: In stock
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