CVN636

Item no.	HY-153615-1mg
Manufacturer	MedChem Express
CASRN	2226732-62-1
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.47
Formula	C19H20FNO4S
Citations	[1]Dickson L, et, al. Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist. ACS Med Chem Lett. 2023 Mar 2;14(4):442-449.<br>[2]Ayscough AP, et, al. Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist. ACS Med Chem Lett. 2023 Mar 2;14(4):442-449.
Smiles	CS(=O)([C@H]1C2=CC=CC=C2OC[C@@H]1NC([C@H](C3=CC=C(C=C3)F)C)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC50 value of 7 nM for hu mGluR7. CVN636 has central nervous system (CNS) permeability[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	377.43
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	mGluR
Isoform	mGluR7
Pathway	GPCR/G Protein; Neuronal Signaling
Manufacturers Product type	Reference compound

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