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Cimdelirsen (sodium)

Cimdelirsen (sodium)

Item no.	HY-153485A-1ea
Manufacturer	MedChem Express
CASRN	2131025-83-5
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C296H415N83Na20O152P20S15
Citations	[1]Bhanot S, Fleseriu M, Geary R, et al. OR27-4 Placebo-Controlled and Open-Label Extension Study of a Novel Hepatic-Targeted Antisense Cimdelirsen (IONIS-GHR-LRx) Under Investigation in Acromegaly Patients. J Endocr Soc. 2022;6(Suppl 1):A526.
Smiles	[Cimdelirsen (sodium)]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ISIS 766720 (sodium); IONIS-GHR-LRx (sodium)
Available
Product Description	Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
Shipping	Room temperature
MolecularWeight	9128.16
Clinical Information	Phase 2
Manufacturers Research Area	Others
Solubility	10 mM in H2O
Target	Small Interfering RNA (siRNA)
Manufacturers Target	Small Interfering RNA (siRNA)
Manufacturers Pathway	Epigenetics
Manufacturers Product type	Oligonucleotides

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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