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HECT E3-IN-1

HECT E3-IN-1

Item no.	HY-153178-50mg
Manufacturer	MedChem Express
CASRN	1810058-52-6
Amount	50 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.37
Formula	C21H26N2O4
Citations	[1]Stefan G Kathman, et al. A Small Molecule That Switches a Ubiquitin Ligase From a Processive to a Distributive Enzymatic Mechanism. J Am Chem Soc. 2015 Oct 7;137(39):12442-5.
Smiles	CC1=C(C(NC/C=C/C(OC)=O)=O)C2=CC(OC)=CC=C2N1C3CCCC3
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	HECT E3-IN-1 (compound 3) is a HECT E3 ligase inhibitor. HECT E3-IN-1 (compound 3) disrupts Ub binding to the noncovalent Ub-binding site of Nedd4-1[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-protein/nucleotide metabolism
MolecularWeight	370.44
Clinical Information	No Development Reported
Manufacturers Research Area	Others
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	E1/E2/E3 Enzyme
Manufacturers Target	E1/E2/E3 Enzyme
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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