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KIF18A-IN-6

KIF18A-IN-6

Item no.	HY-153065-50mg
Manufacturer	MedChem Express
CASRN	2914879-10-8
Amount	50 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	98.56
Formula	C28H37N3O5S2
Citations	[1]COGAN, et al. SPIRO INDOLINE INHIBITORS OF KIF18A. Patent WO2023028564.
Smiles	O=S(C1=CC(C(N2CC3(CCC4(CC4)CC3)C5=CC(NS(CC)(=O)=O)=CC=C52)=O)=CC=C1)(NC(C)(C)C)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	KIF18A-IN-6 (Compound 134) is an orally active KIF18A inhibitor with an IC50 of 0.016 μM against KIF18A microtubule-dependent ATPase activity[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	559.74
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Target	Microtubule/Tubulin
Manufacturers Target	Microtubule/Tubulin
Manufacturers Pathway	Cell Cycle/DNA Damage; Cytoskeleton
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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