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DRP1i27 (dihydrochloride)

DRP1i27 (dihydrochloride)

Item no.	HY-152086A-50mg
Manufacturer	MedChem Express
Amount	50 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.07
Formula	C20H28Cl2N6O
Citations	[1]Rosdah AA, et al. A novel small molecule inhibitor of human Drp1. Sci Rep. 2022 Dec 13;12(1):21531.
Smiles	[H]Cl.CC1=C(NC=N1)CN2C[C@@H]3CC[C@@H](N(C3)CC4=CC=C(O4)C5=NNC=C5)C2.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	DRP1i27 dihydrochloride is a potent inhibitor of human Drp1 (dynamin-related protein 1). DRP1i27 dihydrochloride binds to the GTPase site of Drp1, with hydrogen bonds to Gln34 and Asp218. DRP1i27 dihydrochloride targets Drp1-mediated mitochondrial fission in cell line models and protects against simulated ischemia-reperfusion injury[1].
StorageTemperature	4°C (Powder, sealed storage, away from moisture and light)
Shipping	Room Temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	439.38
Clinical Information	No Development Reported
Manufacturers Research Area	Cardiovascular Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Target	Dynamin
Manufacturers Target	Dynamin
Manufacturers Pathway	Cytoskeleton
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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