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WNK1-IN-1

WNK1-IN-1

Item no.	HY-151545-5mg
Manufacturer	MedChem Express
CASRN	324022-39-1
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.40
Formula	C13H15BrCl2N2O4S
Citations	[1]Rodriguez M, et al. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1. ACS Med Chem Lett. 2022 Sep 23;13(10):1678-1684.
Smiles	O=[N+](C1=CC(S(=O)(C(Cl)(Br)Cl)=O)=CC=C1NC2CCCCC2)[O-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	446.14
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Ser/Thr Protease
Manufacturers Target	Ser/Thr Protease
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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