« Back
Home /
NDT-30805

NDT-30805

Item no.	HY-150965-1ea
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Formula	C23H22N6S
Citations	[1]David H, et al. Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors. ACS Medicinal Chemistry Letters. 2022.
Smiles	S=C1C=C(CC2=NC=CC=C2)NC3=NC(NC4=C5CCCC5=CC6=C4CCC6)=NN13
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	NDT-30805 is a selective NLRP3 inflammasome inhibitor. NDT-30805 is a triazolopyrimidinone derivative and inhibits IL-1β release in PBMCs with an IC50 of 0.013 μM. NDT-30805 can be used for the research of inflammation and innate immunity[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	414.53
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturers Target	NOD-like Receptor (NLR)
Isoform	NLRP3
Pathway	Immunology/Inflammation
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ea

available

Request delivery time