R1-11

Item no.	HY-149715
Manufacturer	MedChem Express
Amount	1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C25H37N5
Citations	[1]Yang WS et al. Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents. Amino Acids. 2017 Sep;49(9):1469-1485.
Smiles	CCCCCCCCN1C(CN(CC)CC)=CC2=CC(C3=CN=C(N)N=C3)=CC=C12
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	R1-11 is an indole ICMT inhibitor with an IC50 of 0.6 μM and has anticancer activity. R1-11 inhibits MDA-MB231 and PC3 cells with IC50s of 2.2 μM and 2.0 μM, respectively[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	407.59
Clinical Information	No Development Reported
Manufacturers Research Area	cancer
Solubility	10 mM in DMSO
Target	ICMT
Manufacturers Target	ICMT
Manufacturers Pathway	GPCR/G Protein
Manufacturers Product type	Reference compound

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