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NSC 694621

NSC 694621

Item no.	HY-147288-25mg
Manufacturer	MedChem Express
CASRN	104857-29-6
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.01
Formula	C13H10N2O2S
Citations	[1]Furdas SD, et al. Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors. Bioorg Med Chem. 2011 Jun 15;19(12):3678-89.
Smiles	O=C1C2=CC=CN=C2SN1C3=CC=C(C=C3)OC
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	258.30
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Histone Acetyltransferase
Manufacturers Target	Histone Acetyltransferase
Isoform	GCN5/PCAF
Manufacturers Pathway	Epigenetics
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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