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NSC-207895

NSC-207895

Item no.	HY-14714-25mg
Manufacturer	MedChem Express
CASRN	58131-57-0
Amount	25 mg
Quantity options	100 mg 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.97
Formula	C11H13N5O4
Citations	[1]Laura Kapitzky, et al. Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action. Mol Syst Biol. 2010 Dec 21;6:451.<br/>[2]Erdenezaya Odkhuu, et al. Lipopolysaccharide downregulates the expression of p53 through activation of MDM2 and enhances activation of nuclear factor-kappa B. Immunobiology. 2015 Jan;220(1):136-41.<br/>[3]Luis A Carvajal, et al. Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia. Sci Transl Med. 2018 Apr 11;10(436):eaao3003.
Smiles	O=[N+](C1=CC=C(N2CCN(C)CC2)C3=[N+]([O-])ON=C31)[O-]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	XI-006
Available
Product Description	NSC-207895 (XI-006), a DNA damaging agent, is an anticancer agent and p53 activator[1][2][3].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	279.25
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
Target	MDM-2/p53
Manufacturers Target	MDM-2/p53
Manufacturers Pathway	Apoptosis
Manufacturers Product type	Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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