Comparison

SW2_152F European Partner

Item no. HY-147058-1mg
Manufacturer MedChem Express
Amount 1 mg
Category
Type Inhibitor
Specific against other
Purity 99.77
Formula C45H62Cl3N7O8
Citations [1]Sijie Wang, et al. A Potent, Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation. Chembiochem. 2021 Jul 1;22(13):2335-2344.
Smiles ClC1=CC(Cl)=CC(C(N[C@@H](CC2=CC(Cl)=C(O)C=C2)C(N[C@@H](C3CCCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN(CC)CC)C(N[C@@H](CO)C(NCC#C)=O)=O)=O)=O)=O)=O)=C1
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Product Description
SW2_152F is a potent, selective chromobox 2 chromodomain (CBX2 ChD) inhibitor with a Kd of 80 nM. SW2_152F displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro[1]. SW2_152F is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
StorageTemperature
-20°C (Powder, protect from light, stored under nitrogen)
Shipping
Blue Ice
Manufacturers Applications
Cancer-programmed cell death
MolecularWeight
935.37
Clinical_Information
No Development Reported
Manufacturers Research_Area
Cancer
Solubility
DMSO : 175 mg/mL (ultrasonic)
Manufacturers Target
Histone Methyltransferase
Pathway
Epigenetics
Manufacturers Product type
Reference compound

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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