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PI3K/Akt/mTOR-IN-2

PI3K/Akt/mTOR-IN-2

Item no.	HY-146751-5mg
Manufacturer	MedChem Express
CASRN	2757804-89-8
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.86
Formula	C17H13F2NO
Citations	[1]Qin J, Sun X, Ma Y, et al. Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway [published online ahead of print, 2021 Dec 31]. Bioorg Med Chem. 2021;55:116594.
Smiles	FC1=CC(F)=CC(C2OCCC3=C2NC4=C3C=CC=C4)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	PI3K/Akt/mTOR-IN-2 is a PI3K/AKT/mTOR pathway inhibitor. PI3K/Akt/mTOR-IN-2 possess anti-cancer effects and selectivity against MDA-MB-231 cells with IC50 value of 2.29 μM. PI3K/Akt/mTOR-IN-2 can induce cancer cell cycle arrest and apoptosis[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	285.29
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	DMSO : ≥ 100 mg/mL
Pathway	Apoptosis; PI3K/Akt/mTOR
Manufacturers Product type	Reference compound

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