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L-Glutamic acid-15N

L-Glutamic acid-15N

Item no.	HY-14608S2-25mg
Manufacturer	MedChem Express
CASRN	21160-87-2
Amount	25 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.0
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. <br>[2]Giorguieff MF, et al. Presynaptic effect of L-glutamic acid on the release of dopamine in rat striatal slices. Neurosci Lett. 1977 Oct;6(1):73-7.
Smiles	OC(CC[C@H]([15NH2])C(O)=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	L-Glutamic acid-15N is the 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	148.12
Clinical_Information	No Development Reported
Manufacturers Research_Area	Neurological Disease
Solubility	H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Isoform	AMPA Receptor; NMDA Receptor
Pathway	Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Manufacturers Product type	Isotope-Labeled Compounds

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