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(S)-Donepezil

(S)-Donepezil

Item no.	HY-14566A-10mM
Manufacturer	MedChem Express
CASRN	142057-80-5
Amount	10mM/1mL
Quantity options	100 mg 10mM/1mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.83
Formula	C24H29NO3
Citations	[1]Lili W, et al. Steady-state plasma concentration of donepezil enantiomers and its stereoselective metabolism and transport in vitro. Chirality. 2013 Sep;25(9):498-505.<br/>[2]Ogura, H., et al., Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol, 2000. 22(8): p. 609-13.
Smiles	O=C1[C@@H](CC2CCN(CC3=CC=CC=C3)CC2)CC4=C1C=C(OC)C(OC)=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(S)-E2020 (free base)
Available
Product Description	(S)-Donepezil is a S-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor[1][2].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	379.49
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Neurological Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Cholinesterase (ChE)
Manufacturers Target	Cholinesterase (ChE)
Manufacturers Pathway	Neuronal Signaling
Manufacturers Product type	Reference compound

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