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TRPM8 antagonist 3

TRPM8 antagonist 3

Item no.	HY-145124-5mg
Manufacturer	MedChem Express
CASRN	2102179-29-1
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Small Molecules
Specific against	other
Purity	99.62
Formula	C13H12N2O4S
Citations	[1]Bianchini G, et al. Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through pKa and LogD Modulation. J Med Chem. 2021 Nov 25;64(22):16820-16837.
Smiles	O=C(N1OCCC1)C2=C(O)N=C(C3=C(O)C=CC=C3)S2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	TRPM8 antagonist 3 is a novel TRPM8 blocker with an IC50 value of 11 nM.
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	292.31
Clinical_Information	No Development Reported
Manufacturers Research_Area	Others
Solubility	DMSO : 25 mg/mL (ultrasonic)
Manufacturers Target	TRP Channel
Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Manufacturers Product type	Reference compound

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