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sEH inhibitor-2

sEH inhibitor-2

Item no.	HY-143294-1ea
Manufacturer	MedChem Express
CASRN	2816102-69-7
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Formula	C23H18N4O3
Citations	[1]Rezaee, E, et al. Design, synthesis, and biological evaluation of some 1,2,3-triazole derivatives as novel amide-based inhibitors of soluble epoxide hydrolase. Med Chem Res 30, 1738–1746 (2021).
Smiles	O=C(C1=CC=CC=C1C(NC2=CC=C(C=C2)CN3C=C(N=N3)C4=CC=CC=C4)=O)O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	sEH inhibitor-2 (compound 5l) is an orally active (predicted percentage absorption: 71.2-88.4%) soluble epoxide hydrolase (sEH) inhibitor, with an IC50 of 0.9 nM. sEH inhibitor-2 can maintain epoxyeicosatrienoic acids (EETs) serum level in high concentrations. sEH inhibitor-2 can be used in study of cardiovascular protection[1].
Shipping	Room temperature
Manufacturers Applications	Neuroscience-Neuromodulation
MolecularWeight	398.41
Clinical Information	No Development Reported
Manufacturers Research Area	Cardiovascular Disease
Solubility	10 mM in DMSO
Target	Epoxide Hydrolase
Manufacturers Target	Epoxide Hydrolase
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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