BPK-25

Item no.	HY-141550-10mM
Manufacturer	MedChem Express
CASRN	2305052-86-0
Amount	10mM/1mL
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.92
Formula	C21H17ClN4O2
Citations	[1]Ekaterina V Vinogradova, et al. An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29.
Smiles	O=C(N(CC1=NC(Cl)=CC=C1)C2=CN=C(C(NC3=CC=CC=C3)=O)C=C2)C=C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1].
StorageTemperature	4°C (Powder, stored under nitrogen)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	392.84
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	DMSO : 150 mg/mL (ultrasonic)
Manufacturers Target	Others
Pathway	Others
Manufacturers Product type	Reference compound

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