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Azide-PEG2-MS

Azide-PEG2-MS

Item no.	HY-140381-250mg
Manufacturer	MedChem Express
CASRN	176520-23-3
Amount	250 mg
Quantity options	100 mg 1 ea 250 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	97.0
Formula	C5H11N3O4S
Citations	[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Smiles	[N-]=[N+]=NCCOCCOS(C)(=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Product Description	Azide-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG2-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	209.22
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	10 mM in DMSO
Target	PROTAC Linkers
Manufacturers Target	PROTAC Linkers
Isoform	PEG Linkers
Manufacturers Pathway	PROTAC
Manufacturers Product type	Reference compound

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