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PTPN22-IN-1

PTPN22-IN-1

Item no.	HY-139693-5mg
Manufacturer	MedChem Express
CASRN	2580935-57-3
Amount	5 mg
Quantity options	100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.89
Formula	C26H21N3O5
Citations	[1]Elizabeth Jaffee, et al. Targeting ptpn22 in cancer therapy. WO2021007491A1.
Smiles	O=C1C2=CC(NC([C@H](C)NC(C3=CC=C(C4=CC=CC=C4)C=C3)=O)=O)=CC=C2NC=C1C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 µM; Ki=0.50 µM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses[1]. From WO2021007491A1 compound L-1.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	455.46
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer; Inflammation/Immunology
Solubility	DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Target	Phosphatase
Manufacturers Target	Phosphatase
Manufacturers Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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