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(Rac)-Etavopivat

(Rac)-Etavopivat

Item no.	HY-139573A-100mg
Manufacturer	MedChem Express
CASRN	2622070-93-1
Amount	100 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.87
Formula	C22H23N3O6S
Citations	[1]Patricia Schroeder, et al. Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease. J Pharmacol Exp Ther. 2022 Mar;380(3):210-219.
Smiles	O=C(C(CO)C1=CC=CC=C1)N2CC3=C(CN(S(=O)(C4=CN=C5OCCOC5=C4)=O)C3)C2
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(Rac)-FT-4202
Available
Product Description	(Rac)-Etavopivat ((Rac)-FT-4202) is an isomer of Etavopivat (HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies[1].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
MolecularWeight	457.50
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Pyruvate Kinase
Pathway	Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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