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Dapsone hydroxylamine

Dapsone hydroxylamine

Item no.	HY-137155-5mg
Manufacturer	MedChem Express
CASRN	32695-27-5
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C12H12N2O3S
Citations	[1]Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768.<br>[2]Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.
Smiles	O=S(C1=CC=C(C=C1)N)(C2=CC=C(C=C2)NO)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	DDS-NOH
Available
Product Description	Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].
Shipping	Room temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	264.30
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	10 mM in DMSO
Manufacturers Target	Drug Metabolite; Reactive Oxygen Species
Pathway	Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Manufacturers Product type	Reference compound

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