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Rabacfosadine

Rabacfosadine

Item no.	HY-13640-50mg
Manufacturer	MedChem Express
CASRN	859209-74-8
Amount	50 mg
Quantity options	100 mg 10 mg 1 ea 1mg 20mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitor
Specific against	other
Purity	99.26
Formula	C21H35N8O6P
Citations	[1]Reiser H, et al. GS-9219--a novel acyclic nucleotide analogue with potent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma. Clin Cancer Res. 2008 May 1;14(9):2824-32.<br/>[2]Thamm DH, et al. Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Na?ve Canine Multicentric Lymphoma. J Vet Intern Med. 2017 May;31(3):872-878.
Smiles	CCOC([C@H](C)NP(N[C@@H](C)C(OCC)=O)(COCCN1C=NC2=C(NC3CC3)N=C(N)N=C12)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GS-9219; VDC-1101
Available
Product Description	Rabacfosadine (GS-9219), a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Cancer-Kinase/protease
MolecularWeight	526.53
Clinical Information	Phase 2
Manufacturers Research Area	Cancer
Solubility	DMSO : 100 mg/mL (ultrasonic)
Target	Nucleoside Antimetabolite/Analog
Manufacturers Target	Nucleoside Antimetabolite/Analog
Manufacturers Pathway	Cell Cycle/DNA Damage
Manufacturers Product type	Reference compound

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