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Cimetidine sulfoxide

Cimetidine sulfoxide

Item no.	HY-136338-5mg
Manufacturer	MedChem Express
CASRN	54237-72-8
Amount	5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	97.0
Formula	C10H16N6OS
Citations	[1] Larsson R, et al. The pharmacokinetics of cimetidine and its sulphoxide metabolite in patients with normal and impaired renal function. Br J Clin Pharmacol. 1982;13(2):163-170.<br>[2]HE Barber, et al. The Transport of Cimetidine Across the Rat Small Intestine in Vitro. B r J Pharmacol. 1979 Jul;66(3):496P-497P.<br>[3] Ryta A. Kuzel, et al. Investigations into the chirality of the metabolic sulfoxidation of cimetidine. Chirality (1994), 6(8), 607-14.
Smiles	O=S(CC/N=C(NC)/NC#N)CC1=C(C)N=CN1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Cimetidine sulphoxide
Available
Product Description	Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment[1].
StorageTemperature	-20°C, 3 years (Powder)
Shipping	Blue Ice
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	268.34
Clinical_Information	No Development Reported
Manufacturers Research_Area	Inflammation/Immunology
Solubility	DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturers Target	Histamine Receptor
Pathway	GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Manufacturers Product type	Reference compound

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