DFHO

Item no.	HY-136277-1mg
Manufacturer	MedChem Express
CASRN	1420815-34-4
Amount	1 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.83
Formula	C12H9F2N3O3
Citations	[1]Wenjiao Song, et al. Imaging RNA polymerase III transcription using a photostable RNA-fluorophore complex. Nat Chem Biol. 2017 Nov;13(11):1187-1194.<br>[2]Hyaeyeong Kim, et al. A Fluorogenic RNA-Based Sensor Activated by Metabolite-Induced RNA Dimerization. Cell Chem Biol. 2019 Dec 19;26(12):1725-1731.e6.
Smiles	O=C(N1C)/C(N=C1/C=N/O)=C\C(C=C2F)=CC(F)=C2O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Available
Product Description	DFHO is a fluorogenic ligand of Corn fluorogenic aptamer. The RNA aptamer, Corn binds DFHO with a Kd value of 70 nM and converts it to a fluorescent form, enabling RNA imaging in cells[1][2].
StorageTemperature	4°C (Powder, protect from light)
Shipping	Room Temperature
MolecularWeight	281.21
Clinical_Information	No Development Reported
Manufacturers Research_Area	Others
Solubility	DMSO : 100 mg/mL (ultrasonic)
Manufacturers Target	Fluorescent Dye
Pathway	Others
Manufacturers Product type	Dye Reagents

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