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DBCO-PEG4-Ahx-DM1

DBCO-PEG4-Ahx-DM1

Manufacturer	MedChem Express
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Amount	1 ea
Item no.	HY-136260-1ea
Targets	Drug-Linker Conjugates for ADC
CASRN	2479378-44-2
eClass 6.1	32169090
eClass 9.0	32169090
Available
Product Description	DBCO-PEG4-Ahx-DM1 is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DBCO-PEG4-Ahx-DM1 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	1297.92
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	Drug-Linker Conjugates for ADC
Isoform	Maytansinoids
Pathway	Antibody-drug Conjugate/ADC Related
Manufacturers Product type	ADC Related

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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