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(S,R,S)-AHPC-PEG1-NH2 (dihydrochloride)

(S,R,S)-AHPC-PEG1-NH2 (dihydrochloride)

Item no.	HY-136008A-10mg
Manufacturer	MedChem Express
CASRN	2341796-83-4
Amount	10mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Formula	C26H39Cl2N5O5S
Citations	[1]Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1.
Smiles	O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCN)=O.Cl.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	VH032-PEG1-NH2 (dihydrochloride)
Available
Product Description	(S, R, S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S, R, S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs[1].
Shipping	Room temperature
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	604.59
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer
Solubility	10 mM in DMSO
Manufacturers Target	E3 Ligase Ligand-Linker Conjugates
Isoform	von Hippel-Lindau (VHL)
Pathway	PROTAC
Manufacturers Product type	Reference compound

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